O-27: Bipolar Disorder in Polycystic Ovarian Syndrome Women

Background: Determining bipolar disorder in polycystic ovarian syndrome (PCOs) women. Materials and Methods: One hundred and ten women with definite diagnosis of PCOS and one hundred and ten age-matched infertile women due to other reasons except for PCOS enrolled in this case-control study. Ten ml fasting venous blood sample obtained to check of fasting glucose, LH, FSH. Height, weight, Waist-to-hip ratio (WHR) checked by an expert technician. A psychiatrist with an experience near thirty years examined all 220 cases in order to determine depression and bipolarity in them. Results: Mean age of each group participants were not significantly different while FBS, LH and LH/ FSH levels were significantly higher in PCOS patients. Eighty eight case were depressed in pco group while 96 were depressed in control group (p=0.03). Bipolar disorder were higher in pco ones in comparison with controls (8 vs. 0, p=0.004). Conclusion: Psychiatric disorders should be considered in PCOS women.